A medical doctor and professor, von Eschscholtz joined the scientific research expedition of Otto von Kotzebue, a Tallinn-born Baltic German. The expedition reached the shores of Northern California in 1816.
San Francisco also hosted the West Coast Estonian Days in 1959, 1967, 1975, 1983, 1993, and 2001. The Estonian Society continues as a member organization of the Estonian League of the West Coast.
With more than 1200 attendees from at least 14 countries and 30 states, and 27 performing groups with over 400 performers, the LEP-ESTO festival showcased Estonian culture for Estonians and Northern California locals alike.
The aim of the program is to collect Baltic books and archival materials, support research and teaching, and raise general awareness of the history and culture of the Baltic states.
The program has an active collaboration with the Vabamu museum in Tallinn, and has attracted many high profile visitors from Estonia and the other Baltic states to the Bay Area.
The San Francisco Pääsukesed participated in the Youth Song and Dance Festival (Noorte laulu- ja tantsupidu) in 2017 in Tallinn.
The San Francisco Estonian Community Choir sang in the Song Festival (Üldlaulupidu) in 2019 in Tallinn.